Modernization and Troubleshooting of the USP Organic Impurity Method for Cetirizine Hydrochloride Tablets: Demonstration of XBridge HILIC Robustness Capabilities Across HPLC and UHPLC Instruments

Library Number:
APNT134925012
Part Number:
720005870EN
Author(s):
Jyotsna Sehajpal and Jacob Fairchild
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
 
 

A modernized version of the USP method for organic impurities in cetirizine HCl tablets has been demonstrated on four different LC systems from two different vendors. Similar results were obtained on the HPLC and UHPLC systems used. These experiments were all performed using the same XBridge HILIC Column, providing confidence that validated methods can be successfully transferred between different LC systems.


Title Format File Size
Download PDF PDF 453.08kB