Lab-Scale Oligonucleotide Purification Using Waters Fraction Manager — Analytical System

Library Number:
APNT134924749
Part Number:
720005923EN
Author(s):
Robert E. Birdsall and Ying Qing Yu
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Technical Notes
Related Products:
 
 

The Waters Fraction Manager – Analytical (WFM-A) provides an analytical scale solution for the isolation and enrichment of therapeutic oligonucleotides from process-related impurities that can impact drug product safety and efficacy. The compact design of the WFM-A readily integrates with Waters low dispersion UPLC systems facilitating small scale workflows that offer high recovery with minimal carry-over. The WFM-A is a fraction collection solution that promotes efficient workflows that are ideal for analytical scale purification, enrichment, and impurity isolation applications.


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