Analysis of Synthetic Cannabinoids Using Ion Mobility Enabled High-Resolution Mass Spectrometry

Library Number:
APNT134924609
Part Number:
720005827EN
Author(s):
Waters
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Technical Notes
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This technology brief assess the feasibility of using collision cross section (CCS) data to facilitate differentiation of two isomeric synthetic cannabinoids.

Collision cross section is a valuable parameter in compound identification. The example illustrated in this note shows the benefit of using CCS to distinguish between isomeric substances and increase specificity. The use of drift time alignment facilitates the removal of interfering ions from both the low and high energy spectra, providing cleaner spectra and consequently reducing the occurrence of false positive identifications.


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