USP Method Modernization Using “Equivalent L/dp” and “Equivalent N” Allowed Changes with CORTECS C8 and CORTECS UPLC C8 Columns

Library Number:
APNT134886223
Part Number:
720005666EN
Author(s):
Thomas Swann and Jennifer M. Nguyen
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
 
 

This application illustrates two approaches for making allowed changes to an isocratic USP method involving modern column particles such as that found in solid-core CORTECS Columns.

Using the “equivalent L/dp” guideline is an easy way to modernize a USP method and greatly improve the speed of analysis. With the “equivalent N” guideline, the analyst can realize still further analysis speed improvements from even shorter, highly efficient columns in the CORTECS family.

 


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