Strategies for Improving Impurity Isolation Using Large Volume Loading and Easy Method Development in Preparative Chromatography

Library Number:
APNT134858169
Part Number:
720005476EN
Author(s):
Jo-Ann M. Jablonski, Andrew J. Aubin, Wendy Harrop
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
 
 

The isolation and purification of impurities associated with the production of a variety of consumer products must be properly identified and characterized before these commodities can be sold to customers. Using large volume injections, focused gradients, and a change in column selectivity, we have shown that it is possible to effectively isolate a contaminant with excellent purity. This straightforward approach to impurity isolation is easy to adopt for many types of applications.


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