Leveraging LC-MS in Therapeutic Drug Monitoring Development
Date & Time: Monday, September 25th, 9:40 am - 10:30 am (50 minutes)
Location: Room Swan, Kyoto International Conference Center
Expanding the Role of LC-MS/MS in Therapeutic Drug Monitoring (TDM)
Professor Yusuke Tanigawara,
Keio University School of Medicine, Japan
Modern TDM has grown to cover a diverse selection of drugs ranging from small molecules to biologics. In this workshop, we will discuss the utility and benefit of LC-MS/MS in the application of TDM.
TDM by LC/MS- Single Analyte, Multiplexing and Novel Drugs
Gareth Hammond, Technical Manager,
Clinical Scientist Operations, Waters Corporation, United Kingdom
This talk will take you through the principles, history and future of TDM using LC-MS/MS technology. Starting at the beginning with the development of the first single analyte immunosuppressant assay for tacrolimus (FK506). The specificity and selectivity of LC-MS/MS can simplify the development of multi-analyte (multiplex) panels, such as anti-depressants, antiepileptics and antifungals. The presentation will conclude with a look to the future and new TDM applications for anti-cancer drugs and the challenges to be addressed and overcome when analysing monoclonal antibodies.
Chair: Jose Costro-Prez, Waters Corporation
* To attend the Waters Workshop, you also need to register for IATDMCT 2017.