Whether your scientific focus is on biopharmaceutical characterization, metabolite profiling, forensic toxicology, food or environmental analysis, chemical industry research or proteomics studies, Xevo® G2 QTof provides the highest quality information, enabling you to make the right decisions, quickly and confidently.
The Xevo G2 QTof mass spectrometer, with UPLC®/MSE and QuanTof technology, offers exceptional levels of sensitivity, selectivity, in-spectrum dynamic range, speed of analysis, quantitative accuracy and exact mass performance simultaneously for any experiment, whether UPLC/MS, MSE or MS/MS. It also delivers UPLC/FastDDA: rapid, automated, intelligent exact mass MS/MS for targeted qualitative analyses as well as isobaric labeling quantitative proteomics experiments.
For the most sensitive, exact mass quantitative and qualitative benchtop MS/MS system
A simple, patented method of unbiased data acquisition that comprehensively catalogs complex samples in a single analysis
UPLC/FastDDA (Fast Data Directed Analysis)
Rapid, automated, intelligent MS/MS data acquisition for targeted qualitative analyses as well as isobaric labeling, quantitative proteomics experiments
Universal Ion Source Architecture
The most extensive range of interface capabilities to service the broadest range of applications
Guaranteed maximum system performance and usability through our implementation of Engineered Simplicity™
The most complete system solutions, backed by superior support, to ensure your continued success
QuanTof technology combines innovative high field pusher and dual-stage reflectron designs with a novel ion detection system in an optimized Tof geometry. This provides a totally new dimension of sensitive, high resolution, exact mass, qualitative and quantitative performance - consistently achievable at UPLC acquisition rates.
QuanTof's high field pusher and dual-stage reflectron, which incorporates high transmission parallel wire grids, reduces ion turnaround times due to pre-push kinetic energy spread and improves the focusing of high energy ions respectively. Together, these innovative technologies deliver the highest levels of Tof performance.
QuanTof delivers exact mass accuracy with high precision across LC peaks, which in turn provides high selectivity and confidence for the detection and identification of components in complex mixtures.
The novel ion detection system combines an ultra-fast electron multiplier and hybrid ADC detector electronics. These technologies provide you with outstanding sensitivity and quantitative performance in a much smaller footprint than you would ever imagine possible.
UPLC®/MSE is a method of data acquisition that records exact mass precursor and fragment ion information, while simultaneously obtaining accurate quantitative profiles from every detectable component in a sample. UPLC/MSE rapidly alternates between two functions: the first acquires low energy exact mass precursor ion spectra; the second acquires elevated energy exact mass fragment ion spectra. This means that every mass is measured and spectra for each component are aligned in retention time. UPLC/MSE records data without discrimination or pre-selection; therefore, your samples are completely catalogued in a single analysis.
UPLC/MSE is a simple, patented method of unbiased data acquisition that comprehensively catalogs complex samples in a single analysis.
UPLC®/FastDDA delivers rapid, automated, intelligent exact mass MS/MS capability for targeted qualitative analyses as well as isobaric labeling strategies in quantitative proteomics experiments.
UPLC/FastDDA intelligently selects ions for MS/MS acquisitions in real time, as components elute from the chromatographic system.
Embedded algorithms rapidly interrogate MS survey spectra and co-eluting precursor ions are selected for MS/MS analysis based on threshold intensity, charge state, and pre-defined exact-mass include/exclude lists. The collision energy for each spectrum is optimized according to precursor charge state and m/z.For maximum efficiency, once high quality MS/MS spectra have been acquired, the system intelligently switches back to survey the MS spectrum for the next set of eligible precursor ions
The Universal Ion Source Architecture of Xevo® G2 QTof allows you to use the widest range of ionization techniques as well as the very latest innovations in ionization technologies. You can quickly change the ion source for an extensive choice in experimental options.
With the Atmospheric Pressure GC (APGC) source you have the capability to perform GC and LC separations on a single MS platform. You’ll benefit from the ability to analyze volatile and semi-volatile compounds of low and intermediate polarity- traditionally analyzed only by dedicated vacuum GC/MS instruments.
The Atmospheric Solids Analysis Probe (ASAP) allows spectra to be rapidly generated from virtually any sample with the minimum of sample preparation.