Xevo G2 QTof

QuanTof Technology
For the most sensitive, exact mass quantitative and qualitative benchtop MS/MS system

UPLC^®/MS^E
A simple, patented method of unbiased data acquisition that comprehensively catalogs complex samples in a single analysis

UPLC/FastDDA (Fast Data Directed Analysis)
Rapid, automated, intelligent MS/MS data acquisition for targeted qualitative analyses as well as isobaric labeling, quantitative proteomics experiments

Universal Ion Source Architecture
The most extensive range of interface capabilities to service the broadest range of applications

Accessibility
Guaranteed maximum system performance and usability through our implementation of Engineered Simplicity™

System Solutions
The most complete system solutions, backed by superior support, to ensure your continued success

QuanTof technology combines innovative high field pusher and dual-stage reflectron designs with a novel ion detection system in an optimized Tof geometry. This provides a totally new dimension of sensitive, high resolution, exact mass, qualitative and quantitative performance - consistently achievable at UPLC acquisition rates.
QuanTof's high field pusher and dual-stage reflectron, which incorporates high transmission parallel wire grids, reduces ion turnaround times due to pre-push kinetic energy spread and improves the focusing of high energy ions respectively. Together, these innovative technologies deliver the highest levels of Tof performance.

QuanTof delivers exact mass accuracy with high precision across LC peaks, which in turn provides high selectivity and confidence for the detection and identification of components in complex mixtures.

The novel ion detection system combines an ultra-fast electron multiplier and hybrid ADC detector electronics. These technologies  provide you with outstanding sensitivity and quantitative performance in a much smaller footprint than you would ever imagine possible.

• Use simple, generic methods
• Take advantage of Ultra Performance Liquid Chromatography
• See every detectable component in your samples
• Get exact mass precursor and fragment ion spectra
• Identify and quantify from a single dataset

UPLC^®/MS^E is a method of data acquisition that records exact mass precursor and fragment ion information, while simultaneously obtaining accurate quantitative profiles from every detectable component in a sample.  UPLC/MS^E rapidly alternates between two functions:  the first acquires low energy exact mass precursor ion spectra; the second acquires elevated energy exact mass fragment ion spectra. This means that every mass is measured and spectra for each component are aligned in retention time. UPLC/MS^E records data without discrimination or pre-selection; therefore, your samples are completely catalogued in a single analysis.

UPLC/MS^E is a simple, patented method of unbiased data acquisition that comprehensively catalogs complex samples in a single analysis.

UPLC^®/FastDDA delivers rapid, automated, intelligent exact mass MS/MS capability for targeted qualitative analyses as well as isobaric labeling strategies in quantitative proteomics experiments.

UPLC/FastDDA intelligently selects ions for MS/MS acquisitions in real time, as components elute from the chromatographic system.

Embedded algorithms rapidly interrogate MS survey spectra and co-eluting precursor ions are selected for MS/MS analysis based on threshold intensity, charge state, and pre-defined exact-mass include/exclude lists. The collision energy for each spectrum is optimized according to precursor charge state and m/z.

The Universal Ion Source Architecture of Xevo^® G2 QTof allows you to use the widest range of ionization techniques as well as the very latest innovations in ionization technologies.  You can quickly change the ion source for an extensive choice in experimental options.

With the Atmospheric Pressure GC (APGC) source you have the capability to perform GC and LC separations on a single MS platform.  You’ll benefit from the ability to analyze volatile and semi-volatile compounds of low and intermediate polarity- traditionally analyzed only by dedicated vacuum GC/MS instruments.

The Atmospheric Solids Analysis Probe (ASAP) allows spectra to be rapidly generated from virtually any sample with the minimum of sample preparation.