Necessity is the mother of mass spectrometry.
When the scientists at the University of Warwick (UK) are in need, they call Waters.
From the latest in analytical instrumentation and software to just needing an ear to listen to their ideas and plans for the future. In one particular case, the necessity involved instrumentation that was only dreamt about. The scientists were studying misfolded proteins, the ones that are thought to create diseases such as Alzheimer’s and Parkinson’s. But traditional instrumentation wasn’t enough to get the job done. The university asked Waters if they could build a shape-selective mass spectrometer. It was a necessity. As luck would have it, Waters had already been working along similar lines. So with input from the scientists, a new mass spectrometer was created. It became known as SYNAPT High Definition Mass Spectrometry or HDMS for short, the first commercial shape-selective mass spectrometry instrument. Originally purchased to study misfolded proteins, it also allows the scientists at the University of Warwick to collect 200 high quality mass spectra in 18 milliseconds.
And that’s how necessity led to a new form of mass spectrometry.