UPLC® Technology was created especially for scientists who seek proven, reliable technology that simultaneously improves laboratory productivity, efficiency, and throughput. With its success demonstrated by thousands of peer-reviewed papers and application notes, and dramatic process improvements, leading companies and institutions around the world have standardized on UPLC/UHPLC for measurable scientific and business benefits.

ACQUITY UPLC H-Class System The ACQUITY UPLC H-Class System is the first UPLC/UHPLC system that delivers the flexibility of quaternary solvent blending with the advanced performance expected of UPLC separations: high resolution, sensitivity and improved throughput.
ACQUITY UPLC I-Class System The highest performing UPLC system ever engineered. With dramatically decreased dispersion for the highest resolution, rapid injection cycles and sample throughput with reduced carryover, it's clearly the superior inlet to any mass spectrometer.
ACQUITY UPLC M-Class System The most reliable and highest performing nano- to microscale instrument available to deliver UPLC-quality (UHPLC) separations ― providing more sensitivity to every laboratory performing LC-MS analyses.
ACQUITY Arc System Easily accepts and replicates methods from any HPLC platform, without compromise. A versatile, modern LC system that delivers HPLC and UHPLC method compatibility at the flip of a switch.
ACQUITY UPLC H-Class Bio Engineered with a bio-inert flow path, the ACQUITY UPLC H-Class Bio System is ideal for orthogonal RP, SEC, IEX, and HILIC quaternary bioseparations.
ACQUITY Advanced Polymer Chromatography System Breakthrough technology for high resolution characterization of polymers. Delivers more information about your polymers faster than ever before.
ACQUITY UPLC System The ACQUITY UPLC System lets you achieve higher UPLC/UHPLC chromatographic resolution and sensitivity and greater throughput using sub-2-µm particle technology. This is the original UPLC system featuring binary solvent management.
PATROL UPLC Process Analysis System Bringing chromatographic analysis to process analytical technology (PAT), this real-time UPLC system is able to detect and quantify complex multiple component samples and final product.
ACQUITY UPLC Systems with 2D LC Technology ACQUITY UPLC Systems with 2D LC/multidimensional LC provide resolution, sensitivity, and productivity for multidimensional applications that is simple to use, easy to implement, and compatible with a wide range of chemistries.
ACQUITY UPLC M-Class System with 2D Technology For protein identifications, quantification, and sequence coverage, 2D technology employs reversed-phase chromatography at pH 10 in the first dimension, followed by reversed-phase chromatography at pH 2 in the second dimension.
ACQUITY UPLC M-Class System with HDX Technology The ACQUITY UPLC M-Class System w/Hydrogen Deuterium Exchange (HDX) Technology and high-resolution MS identifies changes in protein conformation with confidence by stringently controlling temperature sensitive parts of the HDX sample work up.
Open Architecture UPLC Robust UPLC analyses in a familiar workflow for chemists in discovery laboratories are available with the Open Architecture UPLC System’s flat-bed sample manager and open-access software.
Waters Fraction Manager - Analytical The Waters Fraction Manager (WFM-A) is an analytical fraction collector for UPLC systems that minimizes fraction loss and carryover to better manage low volume peaks and allows for efficient collection of small amounts of material for further assays.
ACQUITY QDa Detector ACQUITY QDa Detector is a mass detector built around the needs of analytical scientists for chromatographic analysis. Robust, reliable and requiring no sample adjustments, it integrates with your current LC, ACQUITY UPLC, UPC2 and purification systems.
ACQUITY UPLC Detectors Optical and mass detectors are optimized for UltraPerformance LC separations, with low dispersion characteristics, performance, and high data-acquisition rates.
ACQUITY UPLC Accessories Accessories for the ACQUITY UPLC System allow you to customize instrument performance by managing column temperature, number of columns, and quantity of samples needed to analyze. The cart provides easy mobility.