SQ Detector 2

• IntelliStart™ – monitors your system and automates detector set-up to ensure optimal performance.
• Wide Mass Range – 3000 Da mass range enables analysis of both low and high molecular weight species.
• Versatility – Designed for optimum compatibility with UPLC, UPSFC, HPLC, GC, preparative HPLC and preparative SFC.
• Ion Source Options – offers easy compatibility with the widest range of analytes through the Universal Ion Source architecture.
• OpenLynx™ Open Access Software – optional application manager provides walk-up access to all levels of system user for LC/MS analyses.
• FractionLynx™ – optional application manager provides comprehensive mass directed preparative chromatography applications. Compatible with OpenLynx Open Access to provide walk-up preparative capabilities to system users with all levels of experience.
• ZSpray™ – Waters patented source technology provides exceptional robustness and reliability
• Quantitative Workflow – works for you to automate routine tasks, streamlining generation, review and reporting quantitative data.

IntelliStart™ Technology automates system setup so that non-expert users can acquire data with confidence that the system is operating optimally. 

An integrated system of fluidics, electronics, and software continually monitors system performance. Through a series of diagnostic checks, the MS detector can report when it is ready for use. Any failures trigger a red-light system status, which warns that action may be required before analysis can proceed.

IntelliStart Technology:

• Resolves system alerts
• Auto tunes and calibrates the system, optimized for your analysis
• Automatically generates SIR methods with ease using integrated fluidics
• Reports on your LC/MS system performance

With a mass range of 3000 Da, the SQ Detector 2 makes mass confirmation of large molecules easier than ever before, allowing you to see higher mass peaks and giving you more confidence in your mass assignments.

Raw data collected to 3000 Da.

Deconvoluting the data using MassLynx shows the mass of the intact antibody at approximately 148 kDa.

Prepare – IntelliStart™ and Quanpedia™ enable rapid, automated set-up and checking of the system, coupled with the generation of optimized quantitative methods where all SIR functions are automatically scheduled to maximize performance.

Analyze – Quanpedia automatically generates all of the components of a complete analysis; optimized MS method, UPLC^® gradient, TargetLynx quantification method and a template sample list. During analysis, QCMonitor will actively monitor the data in real time, taking action if any user-specified tolerances are exceeded.

Interpret – QCMonitor proactively checks your data while it’s running, ensuring that your QC criteria are met during analysis, suspending the sample batch acquisition and requesting operator attention, automatically answering the question "Is my data of the required quality?" TargetLynx™ provides automated quantification and reporting, with automated highly visible flags reducing the possibility for error.

Decide – User configurable TargetLynx reports easily let you view results, so decisions can be made based upon the data. TrendPlot enables you to visualize the TargetLynx results over many days, weeks or months; providing valuable information on data trends and long term system performance.

The Universal Ion Source architecture of the SQ Detector 2 allows the widest range of ionization techniques to be utilized as well as the very latest innovations in ionization technologies. So you'll have an unparalleled choice of experimental options and be ready for the challenges of tomorrow.

When you need options and time is critical, the ion sources are quickly interchangeable and ready to use within minutes.

Integral to the Universal Ionization Source, Waters’ patented ZSpray™ technology means that you get optimum performance and excellent reproducibility from your analysis. Providing exceptional resistance to contamination by involatile buffers, the unique dual orthogonal pathway gives superior separation of ions from neutrals, keeping the instrument cleaner for longer. This results in less down-time, higher laboratory efficiency, and better instrument utilization.