Released Glycan Analysis

UPLC Solutions for Glycan Analysis & Characterization

Many protein-based biopharmaceuticals are glycosylated proteins. Consistent glycosylation is a sensitive marker for a well-controlled process. For this reason, uncontrolled changes in protein glycosylation are of great regulatory concern. The relative amounts of the individual glycan structures need to be monitored during process development to establish the stability of the growth and purification steps of manufacturing. The same measurements are required in the development of formulations and stability testing.

Waters' UPLC-based solutions deliver the resolution, sensitivity, and speed for greater reliability in the qualitative and quantitative analysis of protein glycosylation.

  • Overview
  • Components
  • Literature
  • Application Notes