Quantitative/Qualitative (Quan/Qual) Analysis

Accomplish more with Quan/Qual and QTof MS

Quadrupole time-of-flight (QTof) mass spectrometry platforms have long been used in DMPK groups to understand complex metabolic pathways and provide support for key activities, including metabolic hotspot screening, generating preclinical animal and in vitro/in vivo correlation (IVIVC) information, supporting first-in-man dosing, and providing support for regulatory submission.

Advances in sensitivity, detector linear response, and robustness have opened up the possibility for QTof MS platforms to be a viable alternative for use in bioanalysis laboratories with traditional use tandem quadrupole MS platforms (also referred to as triple quadrupole, or QQQ).

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