HILIC for Released Glycans

Robust LC or LC-MS Analyses of Biotherapeutic Glycoproteins

The analysis of complex N- and 0-linked glycans composed of frequently similar and repeating sugar moieties requires a highly discriminating chromatographic method. Hydrophilic liquid interaction chromatography (HILIC), using UPLC, HPLC, or UHPLC columns containing Waters amide bonded, Ethylene Bridged Hybrid Technology (BEH) particles separates compounds based on differing hydrophilicity.

 

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