Waters® ChromScope™ Software, for use on Waters supercritical fluid chromatography (SFC) purification systems, enables fully automated instrument control and facilitates the process of developing SFC methods and purifying samples.
Its simple work-flow-based architecture and intuitive user-friendly interface makes routine chromatographic analysis, reporting, and fraction collection easy. Simple wizards guide users through a stepwise process of creating new sequences, including method screening, purification, and calibration curve building.
ChromScope Software can be used with systems configured for method development and purification and is available with Waters Method Station and Investigator SFC Systems.
Data Analysis and Reporting
ChromScope Software supports both manual and automatic integration for processing chromatograms allowing you to:
Data Security and Compliance
ChromScope Software was designed under GxP guidelines so that data traceability is assured. Secure user accounts may be added as needed, so that all changes and generated data are digitally signed by the user performing the work.
In order to run the instrument, process run results, or collect fractions, methods must be created to define how these operations should be carried out.
Method files fall into three categories:
General instrument settings
Peaks can be created, deleted, and split using manual integration options. End points of the peaks can be dragged and users can manually set the void time using popup menu of chromatogram plot. Manual integration will automatically update the peak calculations in data grid. Manual peak options in tool bar or menu bar behave like toggle button. Once enabled, options will remain active unless disabled explicitly.
The Auto Integration option is used to choose the integration method from the current project and apply it to the data file open in active file tab.
Auto integration settings can be applied:
Supported integration types are:
Supported baseline options are:
ChromScope™ Software allows you to create a sequence of injections by selecting methods, setting run times, injection volumes, and various other run parameters. A sequence can be built by either using the Sequence Editor or the Sequence Wizard.
The Sequence Editor allows you to create a new sequence or modify an existing sequence. Manually create/edit sequences using a table format with each run in the sequence being represented by a row in the table, and each option for a run in the sequence being represented by a column.
The Sequence Wizard can be used to create method screening sequences, calibration curve building sequences or purification sequences. Sequences created through Sequence Wizard will populate the Sequence Editor. Users can then save and add it to the sequence queue for execution.
Quick and custom reporting formats are available.
Quick Report contains a predefined set of fields, which cannot be altered. Custom Report contains set of components which can be altered using Report Template Editor. The report is printed according to template defined by user.
Main components of the Custom Report include: