Developed for integrated UPLC®-MS/MS quantitative applications, the Waters ACQUITY® TQD features the highest levels of tandem quadrupole MS selectivity, robustness, speed, and accuracy.
To maximize the analytical advantages of UltraPerformance LC® (UPLC), the ACQUITY TQD operates at the highest data acquisition rates. When integrated with the ACQUITY UPLC® System, the ACQUITY TQD gives you class-leading analytical detection limits, resolution, and sample throughput for all of your quantitative applications: bioanalysis, ADME screening, food safety, environmental monitoring, clinical, forensic, and more.
Rapid data acquisition capability:
Automated instrument optimization and quantitative method development tools:
Versatile Range of robust ionization options:
Comprehensive software control and applications:
Intelligent Services Delivery Platform
IntelliStart™ Technology automates system setup so that non-expert users can acquire data with confidence that the system is operating optimally.
An integrated system of fluidics, electronics, and software continually monitors system performance. Through a series of diagnostic checks, the MS detector can report when it is ready for use. Any failures trigger a red-light system status, which warns that action may be required before analysis can proceed.
Accurate quantitation of the narrow peak widths typical of UPLC® (2-3 s) demands fast acquisition speeds for sufficient data points per peak (15-20). T-Wave™ (Traveling Wave™) collision cell technology minimizes source-to-detector ion transit times for high-speed data acquisition. Unlike some collision cell designs, the T-Wave collision cell ensures that signal intensity does not fall as acquisition speed increases.
In this example, the chromatographic signal intensity is maintained as MRM acquisition dwell time is reduced from 200 ms (five data points per second) to 5 ms (100 data points per second).
Rapid positive to negative ion mode switching (in only 20 ms) also enables simultaneous analysis of acidic and basic compounds in a single analytical run. Scientists can take full advantage of the speed of UPLC saving valuable analytical time.
When you need to incorporate mass spectrometry into your laboratory, you want your instrumentation to be as versatile as possible to meet your ongoing analytical needs.
Waters’ portfolio of MS technologies provides a broad range of atmospheric pressure ionization (API) sources to allow your laboratory to meet its productivity requirements:
Built on the ZSpray™ API Interface, each of these ionization sources provides the robust performance you expect of your mass spectrometer.
Tandem quadrupole mass spectrometers are versatile instruments that can be used to perform a wide variety of experiments:
The use of two mass analysers provides improved data quality for a wide range of applications: