HPLC Columns

State-of-the-art Reversed-Phase and HILIC HPLC Columns

Waters offers a wide range of analytical and preparative chromatography columns to meet the needs of virtually every application. The Waters Column Advisor recommends the most appropriate column depending on the on the application requirements you need to consider and the column characteristics you are looking for. Separations developed on our analytical columns can be directly scaled up to preparative columns. We supply a wide range of phase chemistries in numerous column dimensions for preparative work to meet your scale-up needs. All chromatography columns meet stringent specifications to ensure excellent performance and column-to-column reproducibility. We also offer a wide range of accessoriesto support these columns.


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CORTECS Columns Based on 1.6 µm and 2.7 µm solid-core particle technology, CORTECS Columns enable you to achieve new levels of efficiency and performance.
XBridge Columns Waters HPLC XBridge BEH Columns for UHPLC/HPLC are stable in extreme conditions, like high pH, for HILIC & reversed phase chromatography HPLC MS method development.
XSelect Columns The proprietary Charged Surface Hybrid (CSH) Technology that powers XSelect Columns improves selectivity and offers the highest possible performance for basic compounds in the acidic, low ionic strength mobile phases commonly used in LC-MS laboratories.
VanGuard Column Protection VanGuard Pre-columns and Cartridges are optimized to protect and prolong analytical column lifetimes without compromising chromatographic performance.
UHPLC Columns Our focused selection of UHPLC columns highlight the performance advantages modern UHPLC instrumentation.
Symmetry Columns Symmetry LC columns manufactured using high purity silica and tightly controlled manufacturing processes to ensure that you receive a column that exceeds the standards for HPLC column performance.
Bioseparations Columns & Consumables Chemistry consumables for the accurate analysis of peptides, proteins, oligonucleotides, glycans and amino acids.
Atlantis Columns Atlantis analytical and preparative columns are the industry-leading solution for polar compound retention.
SunFire Columns SunFire Chromatography Columns are available in analytical and preparative dimensions and feature state-of-the-art bonded-silica designed for high mass loading capability, excellent low pH stability, superior peak shapes, and high efficiency.
XTerra Columns Based upon first generation hybrid (inorganic/organic) particles, the XTerra family of HPLC columns enables chromatographers to perform high pH drug discovery, method development and purification separations.
Nova-Pak Columns The bonded phases of Nova-Pak Chromatography Columns are available in 4µm and 6 µm particle sizes that offer high resolution as well as faster and more efficient chromatography.
Waters Spherisorb Columns Waters Spherisorb Columns are produced in a wide range of particle sizes (3-, 5-, and 10-µm) and bonded phases to meet your chromatographic needs.
Resolve Columns Resolve columns for applications requiring high resolution
µBondapak - Bondapak The unique combination of proprietary silica pretreatment and bonding chemistry makes µBondapak ideal for the separation of acidic, basic and neutral compounds making them widely useful for preparative chromatography.
µPorasil/Porasil Columns µPorasil/Porasil Columns
Waters PAH Columns For an improved analysis of PAH compounds
Protein-Pak Columns HPLC IEX, HIC, Affinity HPLC-based columns intended for high-quality analysis or lab scale isolation of proteins or polypeptides.
Shodex RSPak Columns Polymeric reversed-phase columns for applications requiring broad pH range
BioSuite Columns A family of HPLC columns ideally suited for the isolation, analysis, and characterization of proteins and peptides.
Column Accessories Waters offers a variety of tubings, fittings, column connections, and replacement parts for columns and cartridges.