Quantitative Mass Spectrometry for Chemical

Quantify How Much is in Your Sample

Whether you are developing agrochemicals, cosmetics, consumer products, personal care or fine and speciality chemicals, you need to quantify exactly how much of your compound of interest is present in your sample. The versatile Xevo portfolio of mass spectrometry systems allows you to create customizable and versatile testing environments whether you work in a centralized core facility, where customer needs change every day, or in a dedicated specialist laboratory running multiple parallel analysis.

Waters Xevo Mass Spectrometry Solutions Integrate:
  • Chromatographic systems and mass spectrometers that combine accurate reproducible separations and maximum MS performance with intelligent, easy-to-use laboratory software converting scientific data into useful information.
  • Chemistry consumables that work with your system to maximize sensitivity, increase throughput, and ensure the development of robust methods.
  • Waters Application Support and Global Services partner with you to optimize your laboratory efficiency, help maintain system peak performance, address scientific application challenges and meet your compliance requirements to ensure the success of your laboratory and business.
Trace Detection of Agrochemicals

Trace-level analysis in complex biological and environmental matrices is key to supporting both pre and post product registration activities of new agrochemical products. The compact, high-performance Xevo TQ-XS tandem quadrupole mass spectrometer detects target compounds at trace level concentrations, so samples can be diluted to reduce matrix effects, also allowing the use of smaller sample volumes, so regulatory limits can be met.

Quantify all the metabolites in your sample, and accurately determine the potential toxicological and environmental impact. The Xevo G2-XS QTof analyzes the broadest range of compounds in the most complex samples, helping to reduce the time taken to register a new agrochemical ingredient.

Brochure

Agrochemical Solutions - Accomplish More in an Increasingly Demanding Industry Landscape

Application Notes

Improving the Analysis of Triazole Fungicides in Wheat Straw Samples using UniSpray Ionization with ACQUITY UPC2

Xevo G2-XS QTof Quadrupole Time-of-Flight Mass Spectrometer

Consumer Product Safety Testing

Nitrosamines can potentially be formed in consumer products, cosmetics and personal care formulations, either during manufacture or product storage. To meet the stringent regulatory requirements of the cosmetics industry, they must be quantified below the regulatory limit of 50 μg/kg.

Increased levels of N-nitrosamines have been identified in products over 5 years old.

A direct LC-MS method using a Waters system including the ACQUITY UPLC I-Class with Xevo TQ-S micro, can be used to quantify N-nitrosamines in consumer products below the regulatory limit of 50 μg/kg. This approach offers increased sample throughput and reduced run times and solvent usage.

Application Notes

A Fast Efficient Method to Determine the Presence of Nitrosamines in Cosmetics, Personal Care and Consumer Products

Xevo TQ-S micro Tandem Quadrupole Mass Spectrometer

Characterizing Botanical Extracts in Cosmetics

The use of botanical extracts in cosmetics is challenging due to variability in natural materials. Instrumentation that can analyze a wide range of samples, with a wide range of analytes in each sample is imperative to quantifying and qualifying these compounds.

The Xevo TQD provides easy access to UPLC-MS/MS, maximizes sample throughput, accommodates a wide range of samples and performs trace level analyses. This allows integration into QC processes to make sure you stay within regulatory limits and also to ensure final production information is accurate – a critical step in customer order fulfilment.

Application Notes

Advancing the Characterization and Quality Control of Botanical Extracts with Mass Spectrometry

Xevo TQD Tandem Quadrupole Mass Spectrometer

Contact Waters

Local Offices