Additional classes of biotherapeutics that benefit from Waters UPLC and UPLC/MS characterization technologies, and advanced analytical techniques that support such characterization efforts.
Auto•Blend Plus automates the formulation of mobile phases from reservoirs of pure solvents or concentrated stock solutions. It comes with an ACQUITY UPLC H-Class or H-Class Bio System.
Electron Transfer Dissociation (ETD) MS
Electron-transfer dissociation (ETD) is a method of fragmenting ions in a mass spectrometer. ETD induces fragmentation of cations (e.g. peptides or proteins) by transferring electrons to them.
Host Cell Proteins (HCPs)
Go beyond the uncertain HCP data provided by ELISA assays to LC/MS methodologies that enable identification and quantification of host cell protein product impurities down to low ppm levels.
Obtain superior separations and LC/MS characterization data for synthetic oligonucleotides, from routine mass and sequence confirmation to a more detailed impurity profile analysis.
Following the monograph revision by the U.S. Pharmacopia, Waters has developed an ion-exchange method to separation of oversulfated chondroitin sulfate (OSCS) in heparin sodium.
UPLC/MSE and BiopharmaLynx combine to provide unique capabilities for the separation and characterization of vaccines, reducing the amount of time required for such analyses.